Matt McCormick wrote, “Patients with no history of gambling find themselves overwhelmed with the urge to gamble when their dosages (of Parkinson’s drug pramipexole) cross a particular threshold, sometimes leading them to gamble away their life savings. But when the dosage is reduced, the urge vanishes.” Can Creator tell us what is REALLY going on here?

Here is another example of a local phenomenon being triggered to be perceived, by a drug effect within the brain tissue. So what is happening is that stored preferences and a kind of emotional interpretation and experiencing is stored locally, as a function of cellular memory, and the drug has the ability to change the chemical makeup locally, to trigger the signal from that area of the brain to be perceived with an emergence of the urges and the desire for an activity to satisfy those urges. All is a component of prior experience because this is a primitive, almost reflex action; it is without logic and has a life of its own, and the patient might feel compelled to follow this urge because it has the full attention of the mind during the experiencing, and so it becomes the marching orders, of the moment at least, and will be given a high priority, and perhaps without an ability to self-censor, and therefore have self-control to override it. So what is happening is the suppression of some of the local information while other portions are enhanced, and that is why there is an exaggerated, and even self-destructive, impulse that might hold sway and be honored again and again and again, and lead to painful and life-altering consequences in defiance of reason and logic by the victim. There is a gas pedal being engaged heavily, with no brake that works to counter it, as a consequence of the distortion produced by the drug present in the system.