This description is correct in its broad outlines. The precise sequence and mechanistic basis for initiation of these symptoms is somewhat inaccurate. This is a function of degree of resistance and vulnerability within each victim. The development of central nervous system symptoms is typically a more severe later stage, but this is more a function of the rate of progression of internal damage more than something that can be attributed solely to one aspect of the makeup of the virus and a precise chronology in the sequence of events following the initial infection. This is a most serious complication and indeed can be rapidly fatal and that has been seen over and over again among the infected population. It is a subpopulation who reach this stage early, so when the cases are isolated, this may not be seen happening at all yet. It is more a function of the numbers. When there is a mass of individuals with ongoing infection and little ability to treat these hapless victims and give them medical care, more will worsen to this stage.
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