There are some anatomic differences. It is more in the position of the organs within the torso. There are transpositions that do sometimes happen in humans through genetic variants. The idea of the blue bloods is a kind of intuitive awareness there is an interbreeding of human and extraterrestrial sources and the need for a way to characterize this is in the nature of a kind of shorthand description representing the makeup of the extraterrestrial compared to human. It is the lack of emotion noted, again and again, by witnesses of alien abductions that has created this feeling that they are ice-like and expressionless and inhuman in their aloofness, and that is the reason for this depiction. It is not something that is true for Arcturians, that there is a difference in the actual chemical composition of the blood, for example.
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