DWQA Questions › Tag: nephrotoxic potential
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Type 2 diabetes is becoming an epidemic in civilized countries, with an ever-increasing trend of obesity, hypertension and other related complications like heart disease, kidney disease and peripheral neuropathy. The concern has been raised that relying on medications to lower blood sugar actually does NOT reduce the risk of death from any of the related health complications of diabetes: stroke, heart attacks, infections, and kidney disease. Is this true and if so, can you help us understand why this is so?
ClosedNicola asked 1 day ago • 
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Will lowering both glucose levels and blood pressure with prescription drugs prevent or treat chronic kidney disease?
ClosedNicola asked 1 day ago • 
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There is a clinical investigation reporting that metformin causes a decline in renal function of patients with Type 2 diabetes. It is well-established from prior studies that metformin in diabetics with chronic kidney disease can have life-threatening lactic acidosis, but that is assumed to be the result of an extreme build-up of metformin in the kidney as a result of the kidney disease preventing excretion of the drug. Is that a kind of misleading assumption, almost a red herring, that is actually a warning pointing to nephrotoxic potential of metformin with low-level exposure, as well as having a body-wide metabolic threat at higher concentrations?
ClosedNicola asked 1 day ago • 
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