DWQA Questions › Tag: azithromycinFilter:AllOpenResolvedClosedUnansweredSort byViewsAnswersVotesWhat is the mechanism of Post-acute COVID-19 Syndrome, and what percentage of cases produces such symptoms?ClosedNicola asked 4 years ago • Coronavirus COVID-19349 views0 answers0 votesThe Lancet just published a 96,000-patient registry analysis of multinational clinical data from hospitalized patients with COVID-19 comparing outcomes of four non-randomized treatment groups compared to controls: Chloroquine alone, chloroquine with a macrolide, hydroxychloroquine alone, or hydroxychloroquine with a macrolide. The main endpoints were in-hospital mortality and sustained ventricular tachycardia or ventricular fibrillation. There was no confirmed benefit of any treatment, and each of these drug regimens were associated with decreased in-hospital survival and an increased frequency of ventricular arrhythmias. Despite the fact this was not a careful randomized trial, it has been widely touted by the press, condemning the use of hydroxychloroquine as not only useless but dangerous for COVID-19 therapy. What is your interpretation of these data?ClosedNicola asked 4 years ago • Coronavirus COVID-19251 views0 answers0 votesThe New England Journal of Medicine just published a non-randomized study of hydroxychloroquine coupled with azithromycin in patients with moderate to severe COVID-19 infections, showing no benefit compared to a control group, using intubation or death as endpoints. Can you comment on the prospects for this therapy, in light of this study and your prior endorsement of this treatment?ClosedNicola asked 4 years ago • Coronavirus COVID-19314 views0 answers0 votesIs the recent small study combining azithromycin with hydroxychloroquine in treating coronavirus COVID-19 accurate in reflecting significant clinical benefit due to both anti-inflammatory and antiviral replication activities? Will this be a valuable adjunct in reducing the impact of the pandemic?ClosedNicola asked 5 years ago • Coronavirus COVID-19429 views0 answers0 votes