DWQA Questions › Tag: azithromycin
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What is the mechanism of Post-acute COVID-19 Syndrome, and what percentage of cases produces such symptoms?
ClosedNicola asked 4 years ago • 
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The Lancet just published a 96,000-patient registry analysis of multinational clinical data from hospitalized patients with COVID-19 comparing outcomes of four non-randomized treatment groups compared to controls: Chloroquine alone, chloroquine with a macrolide, hydroxychloroquine alone, or hydroxychloroquine with a macrolide. The main endpoints were in-hospital mortality and sustained ventricular tachycardia or ventricular fibrillation. There was no confirmed benefit of any treatment, and each of these drug regimens were associated with decreased in-hospital survival and an increased frequency of ventricular arrhythmias. Despite the fact this was not a careful randomized trial, it has been widely touted by the press, condemning the use of hydroxychloroquine as not only useless but dangerous for COVID-19 therapy. What is your interpretation of these data?
ClosedNicola asked 4 years ago • 
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The New England Journal of Medicine just published a non-randomized study of hydroxychloroquine coupled with azithromycin in patients with moderate to severe COVID-19 infections, showing no benefit compared to a control group, using intubation or death as endpoints. Can you comment on the prospects for this therapy, in light of this study and your prior endorsement of this treatment?
ClosedNicola asked 4 years ago • 
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Is the recent small study combining azithromycin with hydroxychloroquine in treating coronavirus COVID-19 accurate in reflecting significant clinical benefit due to both anti-inflammatory and antiviral replication activities? Will this be a valuable adjunct in reducing the impact of the pandemic?
ClosedNicola asked 5 years ago • 
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